Abstract Title:

Synergism of antioxidant action of vitamins E, C and quercetin is related to formation of molecular associations in biomembranes.

Abstract Source:

Chem Commun (Camb). 2015 Apr 21 ;51(36):7713-6. PMID: 25851839

Abstract Author(s):

Gabin Fabre, Imene Bayach, Karel Berka, Markéta Paloncýová, Marcelina Starok, Claire Rossi, Jean-Luc Duroux, Michal Otyepka, Patrick Trouillas

Article Affiliation:

Gabin Fabre

Abstract:

Vitamins E, C and polyphenols (flavonoids and non-flavonoids) are major natural antioxidants capable of preventing damage generated by oxidative stress. Here we show the capacity of these antioxidants to form non-covalent association within lipid bilayers close to the membrane/cytosol interface. Antioxidant regeneration is significantly enhanced in these complexes.

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